Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment
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چکیده
منابع مشابه
Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment
Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine monoclonal antibody (h2E2) was characterized for heterogeneity of N-linked glycosylation and disulfide bonds. In addition, charge heterogeneity, which is partially due to the presence or absence of C-terminal lysine on the heavy chains, ...
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ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2015
ISSN: 2164-5515,2164-554X
DOI: 10.4161/21645515.2014.990856